Survey Antibiotics in the Outpatient Treatment of Upper Respiratory Tract Infections

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Published: Sep 17, 2024
DOI: https://doi.org/10.47191/ijpbms/v4-i9-05
Keywords:
Upper respiratory tract infections, antibiotics, interaction.

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Tran Do Thanh Phong
Vo Truong Toan University, Hau Giang, Vietnam
Tran Thi Ngoc Thao
Vo Truong Toan University, Hau Giang, Vietnam
Tran Kim Ngoc
Vo Truong Toan University, Hau Giang, Vietnam
Tran Thien Phu
Vo Truong Toan University, Hau Giang, Vietnam
Nguyen Anh Kiet
Vo Truong Toan University, Hau Giang, Vietnam
Bach Bao Tran
Vo Truong Toan University, Hau Giang, Vietnam
Nguyen Tuong Anh
Vo Truong Toan University, Hau Giang, Vietnam
Pham Thi Tuyet Nhi
Vo Truong Toan University, Hau Giang, Vietnam
Nguyen Nhat Thao Tuyen
Vo Truong Toan University, Hau Giang, Vietnam
Phan Vu Hung
Vo Truong Toan University, Hau Giang, Vietnam
Dr Manjunath. A.B.
Professor, Department of Oral Pathology and Microbiology, Bapuji Dental College and Hospital, Davangere

Abstract

Aim: (1) Survey on the current situation of antibiotic prescription (2) Assess the safety–reasonability of antibiotic prescription.


Subject and Method: A retrospective descriptive study on 300 outpatient prescriptions at Vo Truong Toan University Hospital in 2023 with the diagnosis of upper respiratory tract infection. Several factors associated with unknown antibiotics were analyzed by the logistic regression model.


Result: Cephalosporin antibiotics account for the highest proportion (42.8%), followed by fluoroquinolones (32.8%). Recorded prescriptions with interactions were 113 prescriptions (37.7%). In the total number of prescriptions (n=113), antibiotic interactions occurred according to: the level of drug interactions to Medscape includes close monitoring (75.8%). Next is the mild level (19.4%) and the severe level is (4.8%). The level of drug interactions according to Drugs.com includes the low level (61.8%). Next is the medium level (37.5%) and the dangerous level (0.7%). The most frequent interaction pairs are ciprofloxacin plus methylprednisolone (64/300 prescriptions), levofloxacin plus methylprednisolone (8/300 prescriptions) and ciprofloxacin plus tramadol (9/300 prescriptions).


Conclusion: The most commonly used antibiotic is cephalosporin, which has many pairs of drug interactions that require close monitoring from treating physicians and clinical pharmacists.


 


 

Article Details

How to Cite
Tran Do Thanh Phong, Tran Thi Ngoc Thao, Tran Kim Ngoc, Tran Thien Phu, Nguyen Anh Kiet, Bach Bao Tran, Nguyen Tuong Anh, Pham Thi Tuyet Nhi, Nguyen Nhat Thao Tuyen, Phan Vu Hung, & Dr Manjunath. A.B. (2024). Survey Antibiotics in the Outpatient Treatment of Upper Respiratory Tract Infections. International Journal of Pharmaceutical and Bio Medical Science, 4(9), 743–747. https://doi.org/10.47191/ijpbms/v4-i9-05
Issue
Vol. 4 No. 9 (2024): Volume 04 Issue 09 September 2024
Section
Articles
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This work is licensed under a Creative Commons Attribution 4.0 International License.

References

I. DiPiro JT, G.C. Yee, L.M. Posey (2020), Pharmacotherapy: a pathophysiologic approach, McGraw Hill,

II. Hashmi H., NA Sasoli, A. Sadiq, A. Raziq, F. Batool, S. Raza, Q. Iqbal, S. Haider, S. Umer Jan, MA Mengal, AM Tareen, A. Khalid, F. Saleem ( 2021), "Prescribing Patterns for Upper Respiratory Tract Infections: A Prescription-Review of Primary Care Practice in Quetta, Pakistan and the Implications", Front Public Health, 9, 787933.

III. Higashi T., S. Fukuhara (2009), "Antibiotic prescriptions for upper respiratory tract infection in Japan", Intern Med, 48, (16), 1369-75.

IV. Infectious Diseases Society of America (2012), "IDSA clinical practice guideline for acute bacterial rhinosinusitis in children and adults", Clin Infect Dis, 54, (8), e72-e112.

V. Shulman ST., AL. Bisno, H.W. Clegg, MA. Gerber, E.L. Kaplan, G. Lee, J.M. Martin, C. Van Beneden (2012), "Clinical Practice Guideline for the Diagnosis and Management of Group A Streptococcal Pharyngitis: 2012 Updated by the Infectious Diseases Society of America", Clinical Infectious Diseases, 55, (10), e86-e102.