An Uncommon Tumor in Stomach in A Young Girl

Abstract

Introduction: Gastrointestinal stromal tumours (GIST) are rare tumours of the Gastrointestinal tract. They are the most common mesenchymal tumour of the gastrointestinal tract.  All GISTs are malignant.Among all Gastrointestinal tract malignancies GIST Comprises 0.1- 3%.  The most common location is stomach. They are usually found in elderly and they are not common in pediatric age group.       

Case Report: A girl aged 16 years presented with the history of melena, hematemesis with dyspepsia. Physical examination revealed mild tenderness over right hypochondrium. On examination, multiple hypopigmented patches noted over both upper limbs. CECT abdomen showed a well-defined heterogeneously enhancing predominantly exophytic necrotic soft tissue SOL over the greater curvature of the proximal body of the stomach with intraluminal extension. Her complete blood count and routine biochemical tests were within normal limits. Endoscopic biopsy from the polyploid lesion along the greater curvature show fragmented bits of gastric mucosa involved by a tumour composed of sheets and fascicles of  round to oval cells having eosinophilic to vacuolated cytoplasm and a few spindle cells. Histopathological examination revealed a  mesenchymal neoplasm favouring GIST.. Then wide local excision of the stomach was done and sent for histopathological examination. The stomach mass was diagnosed as Epithelioid GIST which was confirmed by immunohistochemistry.

Conclusion: GISTs are most common mesenchymal tumours of GI tract. They are malignant in nature. The primary treatment of choice is surgery followed by chemotherapy.