Self-Reported Effects of Daily Oral Liposomal Glutathione Supplementation on Skin Appearance, Energy, And Digestive Comfort in Healthy Indian Adults: A Prospective Open-Label Pilot Study
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Abstract
Background: Indians are exposed to environmental and psychosocial oxidative stress that triggers the production of reactive oxygen species (ROS) that systematically deplete the endogenous antioxidant reservoir of glutathione (GSH).
Aim: The present pilot study evaluated the effect of daily oral supplementation with Cellular Prime Liposomal Glutathione (CP Lipo-GSH), formulated using Lipoedge™ technology by West Bengal Chemical Industries Limited (WBCIL), on self-reported skin appearance, energy level and digestive comfort in healthy Indian adults.
Method: Self-reported ratings (0–10 scale; higher = better) for skin look and feel, energy level, and digestive comfort were collected at Week 0 and weekly thereafter for 17 participants who took a 650 mg oral tablet/day.
Results: Of 17 participants, 11 reported improvements in skin look and feel (mean change +1.18 points; p = 0.05), 8 reported improved energy level (mean change +0.65 points; p = 0.301), and 7 reported improvement in digestive comfort, with 5 unchanged and 5 declining (mean change 0.00; p = 1.000). Digestive comfort was fully preserved at the group level.
Conclusion: These preliminary findings indicate that daily CP Lipo-GSH supplementation is associated with a positive trend in self-reported skin appearance in the majority of participants within an Indian consumer population exposed to chronic pollution- and stress-driven oxidative load, with little or no effect on digestive comfort. Larger, controlled trials are required to confirm these observations.
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